Development and Investigation of the Delivery Mode of a Multivalent Bacterial Fish Vaccine in Zambia

Fish farmer stands in pond
Chosa Mweemba/WorldFish

This activity aims to reduce aquaculture losses due to fish mortalities from identified disease-causing agents (Lactococcus garviae, Streptococcus iniae, Streptococcus agalactiae, Aeromonas hydrophila, and Aeromonas veronii). Objectives include identifying pathogens associated with fish mortalities in aquaculture establishments of Lake Kariba; confirming pathogenicity and disease causation through development of experimental infection methods in tilapia; developing and testing autogenous vaccines for Lactococcus garviae, Streptococcus iniae, and/or Streptococcus agalactiae; devising methods of administering autogenous vaccines to fish on farms; and improving the administration of the already developed L. garviae vaccine. Development of technology to manufacture vaccines locally will lead to improved profitability and sustainability of fish production as well as increased resilience to cope with disease outbreaks. Improved productivity can have a direct effect on the pricing of fish, allowing affordable access to fish by vulnerable individuals, including women and children.

Success Story [2022]

Executive Summary of Results and Findings

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An Investigation of Bacterial Pathogens Associated with Diseased Nile Tilapia in Small-Scale Cage Culture Farms on Lake Kariba, Siavonga, Zambia [peer-reviewed journal article]

An International Aquatics Advanced Clinical Rotation Offered Rich Research Opportunities

Reducing Tilapia Losses Through Vaccine Development in Zambia